Invited Speakers
ALeem Siddiqui
Department of Medicine, University of California, San Diego, USA
2017/4/18 10:31:43
Aleem Siddiqui is currently a Professor in the
Division of Infectious Diseases, Department of Medicine, at the University of
California, San Diego. He received his undergraduate and graduate education
from Osmania University, Hyderabad, India and Ph.D., degree from the University
of Kansas Medical Center, Kansas City, KS. He was a postdoctoral fellow at the
University of Colorado Medical School, Denver, CO with Dr. Ray Erikson followed
by a second postdoctoral fellowship with Dr. William S Robinson at Stanford
University, CA. He was instrumental in the first molecular cloning of an
infectious Hepatitis B virus (HBV) DNA at Stanford University in the laboratory
of Dr. Stan Cohen in 1979. He then
joined the University of Colorado Medical School as an Assistant Professor. He
moved to the University of California, San Diego in 2005. His current research
focuses on molecular mechanisms of liver disease pathogenesis associated with
HBV and HCV viral infections. More recent work is related to mitochondrial dynamics
and metabolisms and innate immunity during HBV/HCV infections. The work shows
that HBV/HCV-induced mitophagy triggers events that suppress innate immunity
via massive ubiquitination of MAVS, a key player in interferon synthesis. He is
currently editorial member of several journals including Journal of Biological
Chemistry, and also serves as an Associate editor of PLoS Pathogens.